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KMID : 0379520110270010031
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한국독성학회지
2011 Volume.27 No. 1 p.31 ~ p.36
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Evaluation of Antimicrobial Activity of the Methanol Extracts from 8 Traditional Medicinal Plants
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Kang Chang-Geun
Hah Dae-Sik
Kim Chung-Hui
Kim Young-Hwan
Kim Eui-Kyung
Kim Jong-Shu
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Abstract
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The methanol extract of 12 medicinal plants were evaluated for its antibacterial activity against Gram-positive (5 strains) and Gram-negative bacteria (10 strains) by assay for minimum inhibitory concentration (MIC) and minimum bacterial concentration (MBC). The antibacterial activity was determined by an agar dilution method (according to the guidelines of Clinical and Laboratory Standard Institute). All the compounds (12 extracts) of the 8 medicinal plants (leaf or root) were active against both Gram-negative and Gram-positive bacteria. Gram-negative showed a more potent action than Gram positive bacteria. The MIC concentrations were various ranged from 0.6 ㎍/㎖ to 5000 ㎍/㎖. The lowest MIC (0.6 ㎍/㎖) and MBC (1.22 ㎍/㎖) values were obtained with extract on 4 and 3 of the 15 microorganisms tested, respectively.
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KEYWORD
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Antimicrobial activity, traditional medicinal plants, minimum inhibitory concentration(MIC), minimum bacterial concentration(MBC), methanol extract, agar dilution method
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